43North — It's Happening Here43North Startup Accelerator


43North is an accelerator program that invests $5 million per year to attract and retain high-growth startups in Buffalo, NY.


Portfolio Companies
Venture Capital Raised
Market Value


ShearShare closes $2.3M round of funding shortly after moving to Buffalo

ShearShare closed on $2.3 million of seed funding led by Atlanta-based Fearless Fund and included contributions from local angel investors Jack Greco and Wayne and Mary Bacon; Empire State Development Corp.’s New York Ventures Fund; Portfolia’s FemTech II Fund; Hearst Corp.’s Level Up Ventures, and Chloe Capital, who met Co-Founders Dr. Tye and Courtney Caldwell at 43North […]


43North’s Inspiring Messages for Women

Celebrating Women’s History Month March is Women’s History Month, and each and every day, we cheers to the incredible women who are making history. But, DYK that only 2.2% of all venture capital dollars go to female founders? Yikes. From day one, 43N has committed to changing that statistic, and today, 22% of our portfolio […]


Top Seedz Plan for Growth

Top Seedz has big plans for expansion and growth – all right here in WNY. Catch out this excellent Believe in Buffalo spotlight from WKBW-TV.



43North Presents: 2022 Investment Trends

Jun 8, 2022 at 5:30 pm — Seneca One

Learn about current startup and investing trends, and how you can get involved from the ground up!

About this event

Curious about crypto? Ready to invest but not sure how or where to start? In a follow-up to Angel Investing 101, join 43North and learn about current startup and investing trends, and how you can get involved from the ground up!

Join us as we explore 2022 Investment Trends for Venture Capital. Learn about and join the discussion around trends such as Web3, Crypto, AI / Machine Learning, Climate tech and more.

Free to the public, this event will take place on Wednesday, June 8th at 5:30pm in the Seneca One Auditorium, doors open at 5pm. Networking to follow in the Seneca One Lobby Bar.

Why to Apply Webinar

Jun 29, 2022 at 11:00 am — Virtual

43North invests $5M annually and offers a stack of benefits, including a $1M investment, 1-1 mentorship, connections to investors, free office space, and so much more. Hear what our founders have to say about why you should apply and how our program can help accelerate your growth.

43North’s VP of Portfolio and Selection, Kevin Siskar joined founders Dan Magnuszewski, ACV Auctions, Irfan Khan, Circuit Clinical (43N Y6) and Dr. Tye & Courtney Caldwell, ShearShare (43N Y7) for a discussion and Q&A around topics including:

-Benefits of 43North’s program
-Living and working in Buffalo
-Tips on standing out during the application process


Buffalo Named One of the Top-Five Fastest Growing Startup Cities

York IE recently named Buffalo as the fifth fastest-growing startup city, in America, coming in over cities like Tampa, Dallas, and LA. Local companies that helped Buffalo rise to the top half of this list include Kangarootime (Y4), Circuit Clinical (Y6), Verivend (Y7), ACV Auctions (Y2). But, this is only the beginning for Buffalo and we know firsthand that […]


Circuit Clinical Raises $29M in Series C

Circuit Clinical closed a $29M round as part of its Series C. The round was led by Denver-based Breakout Investment Partners, with contributors including two of Circuit Clinical’s strategic partners, Medidata and Labcorp. READ MORE


Catching Up with the Y7 Cohort

The Buffalo News editorial board caught up with the eight companies who recently joined 43North on the 24th floor of Seneca One. Overall, the founders are digging in, getting to work, and quickly feeling the support of a unique program and community that are rallying around them. Read more