43North Why Buffalo - 43North


Buffalo’s strategic location, infrastructure, and workforce make it a place where startups can truly make an impact. And the support of more than 20 entrepreneurship support programs such as incubators, accelerators, and economic development organizations is accelerating the growth of our ecosystem.

The number of tech-enabled companies has more than doubled in the past decade, and there was over $530M in VC investment raised by Buffalo startups in 2021.

Startups have received investment from some of the most reputable firms across North America, including:

"With no signs of stopping, Buffalo may be the prefect spot for your company" - Inc.

Connected Community

Strategic Location

  • Located within 500 miles of 40% of the continental North American population
  • Over 2,100 warehousing/logistics facilities
  • Just a one-hour flight to New York City, Chicago, Boston, and Philadelphia; direct flights to the West Coast; and a 5-minute drive to the Canadian border
Startup employees

Talented & Affordable Workforce

  • 21 colleges and universities with 105,000+ students
  • Top-tier medical school at the University at Buffalo
  • Award-winning research institutions like Roswell Park Comprehensive Cancer Center and Gates Vascular Institute
  • The cost of living is 5.8% lower than the national average
  • The average wage is 6% lower than the national average

Industry Connections

  • High-tech companies: PostProcess Technologies, Athenex, Campus Labs, Liazon, PLS 3rd Learning, Viridi Parente
  •  7 hospitals within a 5-mile radius of 43North’s headquarters
  •  Esteemed corporates: M&T Bank, Rich Products, Delaware North, Calspan, New Era Cap Company, Moog, Praxair, Fisher Price, Mentholatum, General Mills, North American Breweries, Tops Markets

“Classic architecture, international cuisine, adventurous activities and serious art: this Western New York city is blossoming.”   -