Buffalo startup scene: A bird’s-eye view

With a history of innovation and the momentum of a city on the rise, Buffalo is quickly becoming one of the most attractive places to establish a startup. Don’t believe us? Check out all of these awesome resources available as part of the Buffalo startup community, and know that if you’re an entrepreneur in Buffalo, the city is there for you.


Located in downtown Buffalo, and backed by The University at Buffalo’s School of Management, the Center for Entrepreneurial Leadership serves to provide practicing entrepreneurs and future business owners with the resources needed to successfully run a company. UB recognizes the importance of and recent rise in entrepreneurial interests in the area and wishes to encourage and sustain the ecosystem in place. Among other things, the center offers an array of classes tailored to specific situations, and connects entrepreneurs just starting out with seasoned experts to help them along the way.  


The New York State Center of Excellence in Bioinformatics and Life Sciences (CBLS) offers business consultation and support programs, workforce development, funding and incentives, as well as access to Start-Up NY for companies in the Bioinformatics and Life Science sectors. The center has many in house and partner programs, making it able to connect startups and successful businesses alike to the resources they need to make a difference in their industry. 


“Validate, Challenge, Accelerate, Mentor, Promote.” That is the mantra for VCAMP, a resource and accelerator for digital health startups who plan to make an impact on the healthcare industry. Weather you just have an idea or are starting your company, VCAMP offers mentorship and programs to equip entrepreneurs at every stage of their startup with the tools and resources they need to succeed.

Thomas R. Beecher, Jr. Innovation Center

The Thomas R. Beecher, Jr. Innovation Center is connected to the Trico building and houses more than 100 companies, including those in life sciences, biotech, and social innovation, as well as businesses offering support services like IP attorneys, talent acquisition, sales, and marketing. It is also home to 43North, as well as the Z80 Labs incubator and DIG coworking space. The collaborative and entrepreneurial setting provides an excellent environment for businesses to grow and network. Offering a collaborative work environment for companies of all sizes, the “plug ‘n’ play” space is perfect for entrepreneurs and small businesses who want to focus on growing their business, rather than spending time and resources on managing office details.


CoworkBuffalo is the brainchild of Nick Quaranto, Kevin Purdy, Dan Magnuszewski, and Brian Fending. The idea was to create a cool space for people who are tired of working at home or in coffee shops. They created a collaborative space for those who get more work done by having a place to go with other people around. With individual and group desks, private rooms for phone calls, and stunning views of main street, this is a space almost guaranteed to boost productivity. They also have an in depth breakdown on their website of one of the most important tools for getting work done, coffee.

Buffalo Manufacturing Works

Like 43North, Buffalo Manufacturing Works is an offshoot of Governor Cuomo’s Buffalo Billion initiative. With a $45 million donation to the cause, and EWI at the helm, Buffalo Manufacturing Works is designed to aid the growth of Buffalo manufacturers and to spur and sustain economic growth in the area. Buffalo Manufacturing Works has been a collaborative effort involving hundreds of local manufacturers, and exists to further better the industry and ensure continual economic expansion.

Invest Buffalo Niagara

Invest Buffalo Niagara is a non-profit, privately funded organization with the primary goal of job creation in the Buffalo Niagara region and it’s eight surrounding counties. The organization supports entrepreneurship in the area by collaborating with local businesses, universities, elected officials, and other non-profit organizations in order to further the economic growth in our region.